Research Contributions

Publications, Book Chapters & Patents

A body of work spanning biomimetic polymers, nanomedicine, drug delivery, cryopreservation, and antimicrobial science — published across leading journals in chemistry, pharmacology, and materials science.

Note: Trainees from the Ahmed group are underlined in the original manuscripts. Corresponding authorship is indicated by * next to Ahmed, M.

Published Manuscripts

2025

Peptide Functionalized Nano-Pillared Surfaces with Tunable Antimicrobial and Immunomodulatory Properties

Jahan, S.; Bhayo, A. M.; Uchida, H.; et al.; Ahmed, M.* — ACS Omega, 10, 46, 56680–56691

2025

Antifouling Polymers Functionalized Stimuli-Responsive CNC Composite with Bacterial Detection Capabilities

Doyle, C.; Combita, D.; Dunlop, M.; Ahmed, M.* — Polymers, 17(15), 2007

2025

Cell Penetrating Peptides Functionalized siRNA Nanoparticles Knockdown HER Receptors in Breast Cancer CellsAccepted

Dissanayake, R.; Mishra, V. K. M.; Ahmed, M.* — J. Pharmacol. Exp. Ther.

2025

Self-assembled Peptide Nanoparticle-Mediated Macrophage Polarization Enhances Anticancer Efficacy of Chemotherapeutics in Triple-Negative Breast Cancer

Bhayo, A. M.; Jahan, S.; Ahmed, M.* — ACS Applied Biomaterials, 8, 9, 8325–8340

2025

Intrinsically Fluorescent Nano-Scaled Peptide Aggregates Upon Arginine to Citrulline Swap

Nazeer, N.; Ghimire, A.; Rainey, J. K.; Lubell, W. D.; Ahmed, M.* — Biotechnology & Bioengineering, https://doi.org/10.1002/bit.70073

2025

Cell Penetrating Peptide Mediated Folic Acid Enrichment and Bioavailability

Mishra, V. K. M.; Towner, R.; Rodriguez-LeCompte, J-C.; Ahmed, M.* — ChemBioChem, 2025, e202500242

2025

Antifouling Coatings Inspired By Biological Templates

Doyle, C.; Ahmed, M.* — Macromol. Rapid Commun., 2400932, 1–16

2024

Controlled Self-Assembly of Macrocyclic Peptide into Multifunctional Photoluminescent Nanoparticles

Dissanayake, R.; Nazeer, N.; Zarei, Z.; Bhayo, N.; Ahmed, M.* — J. Pharm. Sci., S0022-3549(24)00516-1

2024

Secondary Structure Stabilization of Macrocyclic Antimicrobial Peptides via Cross-link Swapping

Nazeer, N.; Kooner, N.; Ghimire, A.; Rainey, J. K.; Lubell, W. D.; Erol, D. M.; Ahmed, M.* — J. Med. Chem., 67, 11, 8693–8707

2024

Nanoparticles Mediated Folic Acid Enrichment

Mishra, V. K. M.; Rodriguez-LeCompte, J-C.; Ahmed, M.* — Food Chemistry, 456, 139964

2024

Clinical Advances in TNBCs Treatment: Focus on PLGA Nanoparticles

Towner, R.; Dissanayake, R.; Ahmed, M.* — J. Pharmacol. Exp. Ther., 390(1), 53–64

2024

Chemotherapeutics Loaded Poly(Dopamine) Core-Shell Nanoparticles for Breast Cancer Treatment

Steeves M.; Combita, D.; Whelan, W.B.; Ahmed, M.* — J. Pharmacol. Exp. Ther., 390, 1, 78–87

2024

Elucidating the Role of Optical Activity of Polymers in Protein-Polymer Interactions

Jahan, S.; Doyle, C.; Ghimire, A.; Combita, D.; Rainey, J.K.; Wagner, B.D.; Ahmed, M.* — Polymers, 16(1), 65

2023

Enhanced Cryopreservation Efficacies of Ice Recrystallization Inhibiting NanoGels

Dissanayake, R.; Combita, D.; Ahmed, M.* — ACS Applied Materials & Interfaces, 15, 39, 45689–45700

2023

Metastatic Breast Cancer: Review of Emerging Nanotherapeutics

Dissanayake, R.; Towner, R.; Ahmed, M.* — Cancers, 15(11), 2906

2023

Photo-Iniferter RAFT Polymerization of Optically Active Hydrophilic Vitamin B5 Analogous Methacrylamide

Combita, D.; Pamunuwegedara, H.; Ahmed, M.* — ACS Applied Polymer Materials, 5, 3, 2289–2297

2022

Evaluation of Biological Activities and Medicinal Properties of Honey Drops and Honey Lozenges

Larsen, P.; Ahmed, M.* — Nutrients, 14, 4738

2022

Biomimetic and Hydrophilic Vitamin B5 Analogous Methacrylamide Polymers Prevent Surface Fouling

Combita, D.; Nazeer, N.; Bhayo, A.; Ahmed, M.* — ACS Applied Polymer Materials, 4, 575–585

2021

Antibacterial and Immunomodulatory Activities of Physiologically Stable, Self-Assembled Peptide Nanoparticles

Nazeer, N.; Simmons, J. R.; Rainey, J. K.; Rodriguez-LeCompte, J. C.; Ahmed, M.* — J. Mater. Chem. B, 9, 9041–9054

2021

Thermoresponsive and Antifouling Hydrogels for Radiative Energy Driven Water Harvesting System

Combita, D.; Ahmed, M.* — Materials Chemistry Frontiers, 5, 917–928

2017

Peptides, Polypeptides and Peptide-Polymer Hybrids for Gene Delivery

Ahmed, M.* — Biomaterials Science, 5, 2188–2211

2017

Enhancing the Potency of Nalidixic Acid Towards a Bacterial DNA Gyrase with Conjugated Peptides

Ahmed, M.; Kelley, S. O.* — ACS Chemical Biology, 12, 2563–2569

+ Additional manuscripts from 2009–2016. Full list available upon request or via Google Scholar.

Book Chapters

Nazeer, N.; Ahmed, M.* Peptide-based hydrogels. Natural and Synthetic Hydrogels. Elsevier, 2024. (Invited)
Mishra, V.K.M.; Ahmed, M.* Polymeric Gold Nanoparticles for Gene Delivery. Gold Nanoparticles for Drug Delivery. Elsevier, 2023. (Invited)
Tabatabaei, M.; Ahmed, M.* Enzyme Linked Immunosorbent Assay. Cancer Biology: Methods in Molecular Biology. Springer Nature, 2021. (Invited)
Larsen, P.; Ahmed, M.* Common Cellular Glycans: Biosynthesis, Modifications and Functions in Cancer and Inflammation. GlycoScience 2nd Edition. Elsevier, 2020. (Invited)
Nazeer, N.; Ahmed, M.* Cationic Polysaccharides for Gene Delivery. GlycoScience 2nd Edition. Elsevier, 2020. (Invited)
Nazeer, N.; Ahmed, M.* Polymers in Medicines. Polymer Science and Nanotechnology. Elsevier, 2019, pp. 281–323. (Invited)
Ahmed, M.* Nanomaterials Synthesis. Polymer Science and Nanotechnology. Elsevier, 2019, pp. 361–399. (Invited)
Ahmed, M.; Narain, R.* Synthetic Cationic Polymers for Gene Delivery & Biochemical Assays. Polymers and Nanomaterials for Gene Therapy. Elsevier (Woodhead Publishing), 2016.
Ahmed, M.; Narain, R.* Well Defined Cationic Polymers for Gene Delivery. Cationic Polymers in Regenerative Medicine. RSC Polymer Chemistry Series, 2014.
Ahmed, M.; Narain, R.* Multiple chapters. Chemistry of Bioconjugates. Wiley, 2013.
Ahmed, M.; Narain, R.* Multiple chapters. Engineered Carbohydrate Based Materials for Biomedical Applications. Wiley, 2011.

Patents

PCT/CA2019/051610

Hygroscopic Hydrogels, Methods and Uses Thereof for Water Collection

Innovative hydrogel technology for atmospheric water harvesting using thermally responsive, antifouling materials.

✓ Patent Granted · Jan 2026
PCT/CA2021/050815

Methods and Uses for Restoring, Solubilizing and Stabilizing Polypeptides

Platform for recovering and stabilizing denatured or aggregated proteins using amphipathic polymer excipients.

Filed · Jun 2021
Patent 08953763US

Composition and Methods for Cryopreserving Cells

NanoGel-based approach to cryopreservation with enhanced ice recrystallization inhibition for cell-based products.

Submitted · Jul 2023
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